Composition of Cough, The active compound is codeine phosphate hemihydrate. Each and every ml of oral Alternative is made up of 2 mg of codeine phosphate hemihydrate.
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chlorpromazine will lessen the extent or outcome of codeine by affecting hepatic enzyme CYP2D6 metabolism. Use Warning/Watch. Helps prevent conversion of codeine to its Energetic metabolite morphine
Codeine is contraindicated in sufferers who're regarded to become ultrafast CYP2D6 metabolisers: Codeine is transformed in its active metabolite morphine with the hepatic isoenzymes CYP2D6, several of which exist with genetic polymorphisms.
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Pregnancy. It's not identified if or how dextromethorphan could affect pregnancy or hurt an unborn little one. Inform your Health care service provider If you're or program to be pregnant.
Retailer at place temperature from light and moisture. Tend not to retailer in the toilet. Tend not to freeze liquid forms of this medication.
methylene blue and codeine each maximize serotonin concentrations. Avoid or Use here Alternate Drug. If drug blend should be administered, observe for proof of serotonergic or opioid-associated toxicities
clomipramine decreases results of codeine by impacting hepatic enzyme CYP2D6 metabolism. Use Caution/Keep an get more info eye on. Prevents conversion of codeine to its active metabolite morphine.
The codeine might enhance frequency of seizures in patients with seizure disorders, and will increase possibility of seizures transpiring in other medical configurations linked to seizures; watch clients having a historical past of seizure Diseases for worsened seizure Management throughout therapy
It truly is mysterious if guaifenesin or dextromethorphan passes into breast milk. Talk to your physician in advance of breastfeeding.
clobazam decreases consequences of codeine by influencing hepatic enzyme CYP2D6 metabolism. Use Warning/Monitor. Stops conversion of codeine to its active metabolite check here morphine.
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